Inocul8 is a dry, free-flowing formula consisting of non-pathogenic, heterotrophic aerobic and anaerobic microorganisms, dominated by nitrifiers and denitrifiers, for the purpose of establishing comprehensive biological filtration in recirculating ecosystems. Per unit mass applied, Inocul8 is more effective at reduction of nitrogen compounds than is Remedi8 (which is more effective at reduction of latent organic matter, in general, than is Inocul8); accordingly, Inocul8 may be utilized to combat acute spikes in concentrations of ammonia, nitrite, and/or nitrate.